Keratin 8 pseudogene 25 (KRT8P25)

Keratin 8 pseudogene 25 (KRT8P25) is classified as a pseudogene, meaning it is a segment of DNA that resembles a functional gene but is generally non-functional and does not produce a functional protein product. Pseudogenes arise from gene duplications or retrotransposition events, and while they may share sequence similarity with their parent gene—in this case, keratin 8 (KRT8)—they do not have the same biological function. KRT8P25 is located on chromosome 3 (chr3:87323268-87324723, hg38). It has no established functional role, disease associations, or evidence of being a protein-coding region, receptor, enzyme, or other therapeutic target. There are no known drugs that interact with this pseudogene, nor does it serve as a biomarker or have known implications in safety or therapeutic challenge. It should not be confused with the functional gene KRT8, which encodes a type II keratin involved in the cytoskeletal structure of epithelial cells.

Other names

keratin 8 pseudogene 25KRT8P25