Keratin 8 pseudogene 33 (KRT8P33)

Keratin 8 pseudogene 33 (KRT8P33) is a pseudogene in the human genome associated with the KRT8 gene, which itself encodes the cytoskeletal protein keratin 8. Pseudogenes are genomic DNA sequences similar to normal genes but are nonfunctional; they typically arise from gene duplication or retrotransposition events and are often unexpressed or encode nonfunctional RNA or protein products. The KRT8P33 pseudogene does not encode a functional protein and does not have established roles in cell biology, disease, or as a therapeutic target. Its presence reflects the complex evolutionary history and gene family expansions in the keratin gene family. Because it is a pseudogene, it is not a druggable or therapeutic target, has no interacting drugs, no disease biomarker status, and no established role in human disease or physiology. The gene is included in systematic nomenclature of keratin pseudogenes for completeness but lacks functional biological relevance.

Other names

KRT8P33