Keratin 83 (KRT83)

Keratin 83 (KRT83) is a type II hair keratin, a basic structural protein that forms part of the keratin gene family and heterodimerizes with type I keratins to create intermediate filaments in hair and nails. It is primarily expressed in the hair follicle cortex and is crucial for the structural integrity and elasticity of the hair shaft. Mutations in KRT83 are associated with hair disorders such as monilethrix, resulting in brittle, beaded hair that breaks easily[1][3][5][6][7][8].

Other names

hair keratin K2.10hard keratin type II 3Hb-3HB3hHb3K83keratin 83, type IIkeratin, hair, basic, 3keratin-83KRT83_HUMANKRTHB3type II hair keratin Hb3type-II keratin Kb23