Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Keratin-associated protein 10-3 (KRTAP10-3)
- Target
- KRTAP10-3
- Molecular classification
- Other, Keratin-associated protein, Structural protein
01
Overview
Keratin-associated protein 10-3 (KRTAP10-3) is a member of the keratin-associated protein (KAP) family, which plays a key structural role in hair fiber formation. These proteins create a matrix that integrates with keratin intermediate filaments, providing the structural rigidity and resistance of hair shafts. KRTAP10-3 belongs to the high-sulfur subgroup of KAPs and is found within an intronless gene cluster on human chromosome 21q22.3. Its main function is the cross-linking with abundant cysteine-rich hair keratins via disulfide bonds, essential for the mechanical properties of hair. KRTAP10-3 is not currently considered a receptor, enzyme, or a typical therapeutic target, but it is important in hair biology and structure[1][2].
- Other names
- KAP10.3KAP18-3KAP18.3KRTAP10.3KRTAP18-3KRTAP18.3keratin-associated protein 18-3keratin-associated protein 18.3high sulfur keratin-associated protein 10.3
02
Biological functions
Structural integrity of hair shaftDisulfide cross-linking with keratinsFormation of rigid hair fibers
03
Disease associations
Other (some associations reported with skin and hair conditions, e.g. features of hair formation; occasionally mentioned in context of diseases such as Nodular Basal Cell Carcinoma, but not as a causal target)
Beyond the preview
Go deeper on Keratin-associated protein 10-3 (KRTAP10-3).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Keratin-associated protein 10-3 (KRTAP10-3).