Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Keratin-associated protein 21-1 (KRTAP21-1)
- Target
- KRTAP21-1
- Molecular classification
- Other (It is not a receptor, ion channel, enzyme, transporter, transcription factor, or any common drug target class—it is a member of the keratin-associated protein family[1][2][4].)
01
Overview
Keratin-associated protein 21-1 is one of several structural proteins that form a matrix embedding keratin intermediate filaments in hair and wool fibers[1][2][4]. These proteins, rich in glycine and tyrosine, contribute to fiber properties such as water absorption and texture. KRTAP21-1 is expressed primarily in hair and wool-producing cells and plays a role in determining wool yield and fiber traits in sheep; its variation is associated with wool production traits and may serve as a genetic marker in animal husbandry[1]. There is no indication of therapeutic roles, disease associations, or pharmacological targeting in humans.
- Other names
- KRTAP21-1KAP21.1keratin-associated protein 21-1
02
Biological functions
Structural component of hair and wool fibersInteracts with keratin intermediate filaments to provide strength and hydration capacity to fibers[1][2]
03
Disease associations
Other (No known direct roles in human diseases; may have genetic marker potential in animal breeding for wool yield[1].)
04
Biomarkers
Wool yield (in sheep: genetic variation in KRTAP21-1 can serve as a marker for wool yield improvement in breeding programs[1].)
Beyond the preview
Go deeper on Keratin-associated protein 21-1 (KRTAP21-1).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Keratin-associated protein 21-1 (KRTAP21-1).