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Target intelligence / Profile preview
Keratin-associated protein 3-3 (KRTAP3-3)
- Target
- KRTAP3-3
- Molecular classification
- Other, Structural protein, Keratin-associated protein
01
Overview
Keratin-associated protein 3-3 (KRTAP3-3) is a member of the keratin-associated protein family, specifically the high-sulfur KAP subfamily, found in humans. These proteins form a matrix with keratin intermediate filaments, providing strength, rigidity, and resilience to the hair shaft through extensive disulfide bonding. The correct function and expression of KRTAP3-3 are critical for the formation and physical properties of hair fibers, but it is not known as a therapeutic target, disease biomarker, or drug target[4].
- Other names
- KAP3.3KRTAP3.3High sulfur keratin-associated protein 3.3Keratin-associated protein 3.3high sulfur keratin-associated protein 3.3
02
Biological functions
Structural integrity of hair fiberFormation of hair shaftInteraction with keratin intermediate filaments
03
Disease associations
Other (implicated in hair/fiber characteristics)
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