Target intelligence / Profile preview

Keratin associated protein 3-4, pseudogene (KRTAP3-4P)

Target
KRTAP3-4P
Molecular classification
Other (pseudogene), Keratin-associated protein family (by sequence similarity, but this specific locus is a pseudogene[1][6][7])
01

Overview

Keratin associated protein 3-4, pseudogene (KRTAP3-4P) is a non-coding, non-functional pseudogene in the human genome. It is related by sequence to the keratin-associated protein (KAP) family, which encodes structural proteins found in the matrix surrounding keratin intermediate filaments in the hair shaft[1][6][7]. Unlike functional KAP genes, KRTAP3-4P does not produce a protein or have a known biological function. The KAP gene cluster is characterized by high sequence diversity and rapid evolution, with numerous pseudogenes dispersed among functional genes[6][7]. KRTAP3-4P is not known to play a role in disease, drug response, or as a biomarker, and is not considered a therapeutic target. If you are searching for a drug target, this locus is not considered relevant. If you require information on functional KAP proteins, a target such as Keratin associated protein 3-3 (KRTAP3-3) or related functional family members may be more applicable[2].

Other names
KAP3AKRTAP3P1Keratin associated protein 3 pseudogene 1Keratin-associated protein 3A pseudogeneKRTAP3-4P

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