Keratin associated protein 9-11, pseudogene (KRTAP9-11P)

Keratin associated protein 9-11, pseudogene (KRTAP9-11P) belongs to the extensive family of keratin-associated proteins (KAPs), which, together with keratin intermediate filaments, constitute the main structural proteins in hair and wool. The "pseudogene" designation indicates this gene is likely disrupted due to mutation and does not code for an active protein product; thus, it lacks biological or pathological function[2][3]. The broader KRTAP subfamily 9 proteins are noted for high cysteine content (classified as ultra-high sulfur group) and may contribute to the structure and mechanical properties of hair fibers, though pseudogenes in this locus, like KRTAP9-11P, do not play an active role in these processes[2]. If a therapeutic or scientific request is for an actionable protein, KRTAP9-11P and variants with “pseudogene” in their name are not considered valid therapeutic targets. They are sometimes cataloged for evolutionary and genomic studies, but not as functional receptors, enzymes, or therapeutically actionable entities[2][3].

Other names

KAP9AKeratin-associated protein 9-11 pseudogeneKRTAP9-11P

None applicable (no mechanism as it is not functional)