KH-type splicing regulatory protein pseudogene 1 (KHSRPP1)

KH-type splicing regulatory protein pseudogene 1 (KHSRPP1) is a **pseudogene** of the KHSRP gene, located in the human genome. As a pseudogene, KHSRPP1 does **not encode a functional protein** and is not regarded as a therapeutic target such as a receptor, enzyme, transporter, or signaling protein[2]. Pseudogenes like KHSRPP1 arise from duplication or retrotransposition events and may be transcriptionally silent or generate non-coding RNAs. They can sometimes play regulatory roles at the RNA level—such as competing for shared microRNAs or stability factors with their parent gene—but there is currently **no direct evidence that KHSRPP1 has a well-characterized biological function, disease association, or therapeutic relevance**[5][2]. The canonical KHSRP protein (not the pseudogene) acts as an RNA-binding protein with roles in mRNA splicing, degradation, and regulation of cell signaling and immune responses, but these functions do **not** apply to KHSRPP1[1][3][4]. Key points: - **KHSRPP1** is *not* a protein or functional RNA gene, but a non-coding genomic remnant. - It is *not* considered a therapeutic target. - It is a "pseudogene," not a member of protein families such as receptor, enzyme, transporter, or transcription factor. - There are no known drugs, biomarkers, or disease associations directly related to KHSRPP1. - The scientific or therapeutic literature on KHSRP pseudogenes is extremely limited and predominantly theoretical. If you are interested in the functional protein (KHSRP/FUBP2), not the pseudogene, KHSRP is a multifunctional RNA-binding protein implicated in mRNA decay, splicing, immune response, and cancer[1][3][4]. If you require information about the **protein-coding KHSRP** rather than this pseudogene, please specify.

Other names

KH-type splicing regulatory protein (FUSE binding protein 2) pseudogeneKHSRPP1