Kidney and heart

The term 'Kidney and heart' refers to two primary organ systems in the human body rather than a specific molecular target such as a receptor, enzyme, or ion channel. The kidneys are essential for filtering waste products from the blood and maintaining electrolyte balance, while the heart serves as the central pump of the cardiovascular system. While these organs are the sites of action for numerous therapeutic classes—such as SGLT2 inhibitors in the kidney and beta-blockers in the heart—the organs themselves do not constitute a singular, discrete biochemical target for drug discovery. In clinical medicine, the interplay between these two systems is often discussed in the context of cardiorenal syndrome, where dysfunction in one organ leads to dysfunction in the other. Because 'Kidney and heart' is an anatomical and physiological classification rather than a molecular one, it is considered an incorrect entry for a specific therapeutic target molecule.

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