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The query describes a therapeutic strategy from traditional Chinese medicine (TCM) rather than a discrete molecular entity or receptor. In TCM, "modulation of kidney function" involves complex herbal formulations and interventions aimed at restoring balance and treating chronic kidney diseases. These strategies commonly target processes such as oxidative stress, inflammation, extracellular matrix deposition, and tissue fibrosis, often working through multiple overlapping biological pathways with pleiotropic herbal mixtures. Although TCM shows promise as an adjunctive or alternative therapy in chronic kidney disease management, this is a systems-based therapeutic philosophy rather than a molecular target. Therefore, it does not map to any canonical molecular target but reflects a theory of holistic treatment and kidney function regulation by integrated herbal regimens.
Multi-component synergy on oxidative stress, inflammation, autophagy-apoptosis modulation, NF-κB and Nrf2 pathway targeting, TGF-β1/MAPK inhibition, HIF stabilization
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