Kidney system function

"Kidney system function" describes the collective physiological processes performed by the kidney organ, including regulation of fluid and electrolyte balance, acid-base homeostasis, removal of metabolic waste, and secretion of hormones involved in controlling blood pressure and erythropoiesis. These functions are executed by a coordinated interplay of molecular targets such as transporters, ion channels, receptors, and enzymes expressed in more than 26 specialized renal cell types organized into nephrons and associated structures. As such, "kidney system function" is not a specific molecular entity or drug target, but an aggregate role of the kidney organ comprised of numerous specialized proteins and cell types[1][4][5][6][7].