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Target intelligence / Profile preview
KIF23 and PAQR5 antisense RNA 1 (KIF23-AS1)
- Target
- KIF23-AS1
- Molecular classification
- Other (Antisense long non-coding RNA)
01
Overview
KIF23 and PAQR5 antisense RNA 1 (abbreviated as KIF23-AS1, also known as LINC02896) is a long non-coding RNA (lncRNA) transcribed from the region antisense to the KIF23 and PAQR5 gene loci. Antisense RNAs like KIF23-AS1 do not encode proteins but can regulate gene expression at transcriptional or post-transcriptional levels, often impacting their associated sense gene, in this case potentially affecting KIF23 or PAQR5 expression. Functional roles for antisense RNAs include modulation of mRNA stability, chromatin remodeling, and influencing translation or degradation of their target transcripts. KIF23-AS1 is not recognized as a druggable target (e.g., receptor, enzyme, transporter), and current evidence does not link it directly to established therapeutic targeting or specific disease roles. There are no known drugs, mechanisms of action, or safety concerns reported for KIF23-AS1, nor is it listed as a biomarker. Its involvement in biological processes or diseases is speculative, based on the general functions of antisense lncRNAs[1].
- Other names
- LINC02896KIF23-AS1
02
Biological functions
Regulation of gene expressionEpigenetic modulationPossible cis- or trans-acting regulation
03
Disease associations
Other (Potential, but not well-established; antisense RNAs may be implicated in various diseases if they regulate disease-associated genes)
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