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KIF9 antisense RNA 1 (KIF9-AS1)
- Target
- KIF9-AS1
- Molecular classification
- Long non-coding RNA (lncRNA), Antisense RNA
01
Overview
KIF9 antisense RNA 1 (KIF9-AS1, FLJ39534) is a long non-coding RNA gene, transcribed from the region antisense to the KIF9 gene on the human genome[3]. Long non-coding RNAs (lncRNAs) are a class of RNA molecules larger than 200 nucleotides in length that do not encode functional proteins but can regulate gene expression at multiple levels, including chromatin modification, transcription, and post-transcriptional processing. The biological role and disease associations of KIF9-AS1 are currently not well defined in the scientific literature[3]. Do not confuse KIF9-AS1 (an lncRNA) with the protein-coding gene KIF9 (Kinesin family member 9), which encodes a kinesin motor protein important for microtubule-based transport and has established roles in sperm flagellar function and cell motility[1][2]. KIF9, but not KIF9-AS1, has been discussed as involved in male infertility and podosome regulation[1][2].
- Other names
- FLJ39534KIF9-AS1KIF9 antisense RNA 1
02
Mechanism of action
none known
03
Biological functions
Not well characterized; likely involved in gene regulation through RNA-mediated mechanisms, possibly influencing the expression of the neighboring KIF9 gene. No confirmed functions such as signaling or molecular transport
04
Disease associations
Not established; there are no current reports of KIF9-AS1 being directly implicated in any specific disease
05
Safety considerations
none known
06
Interacting drugs
none known
07
Biomarkers
none established
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