Kinase suppressor of ras 1 pseudogene 1 (KSR1P1)

Kinase suppressor of ras 1 pseudogene 1 (KSR1P1) is a pseudogene and does not encode a functional protein. It is annotated based on sequence similarity to KSR1, a scaffold protein involved in the RAS/RAF/MEK/ERK pathway, but KSR1P1 itself has no known protein product or direct role in cellular signaling or disease. Pseudogenes like KSR1P1 typically arise from gene duplication or retrotransposition and can sometimes regulate their protein-coding homologs at the RNA level, but there is no evidence that KSR1P1 functions in this capacity[1]. KSR1P1 is not considered a therapeutic target, is not a functional gene product, and is best referred to as a pseudogene. Information about KSR1 (without the "P1" suffix) concerns a genuine protein with multiple important roles in cell signaling and disease, but KSR1P1 should not be confused with it[1].

Other names

KSR1 pseudogene 1KSR1P1