Target intelligence / Profile preview

KRT73 antisense RNA 1 (KRT73-AS1)

Target
KRT73-AS1
Molecular classification
Long non-coding RNA (lncRNA)
01

Overview

KRT73 antisense RNA 1 (KRT73-AS1) is a long non-coding RNA gene located within the cytogenetic region 12q13.13[4]. This RNA is transcribed antisense to the KRT73 (Keratin 73) coding sequence. While the function of KRT73-AS1 has not been fully elucidated, it is classified as a lncRNA, which generally means it may have roles in regulating gene expression at the transcriptional or post-transcriptional level[2][4]. There are currently very few direct studies linking KRT73-AS1 to specific biological pathways, diseases, or therapeutic processes. Notes: - The KRT73-AS1 gene should not be confused with KRT73, which encodes Keratin 73, a protein involved in hair follicle physiology[1][5]. - KRT73-AS1 appears in the GWAS catalog as an lncRNA, with a few reported associations but nothing that meets criteria for high-confidence disease or therapeutic target status as of the current literature[4]. - The field of lncRNAs is rapidly evolving; more functions or disease roles could be uncovered with future research. KRT73-AS1 is best regarded as a long non-coding RNA of uncertain function, potentially of interest as a biomarker, but with no evidence for direct therapeutic targeting at present[2][4][6].

Other names
KRT73-AS1KRT73 antisense RNA 1
02

Biological functions

Not fully clarified; likely involved in transcriptional or post-transcriptional regulation as with other lncRNAs[2][4]
03

Disease associations

The gene is listed in the GWAS Catalog but without currently strong, widely confirmed disease associations[4]. Other sources discuss lncRNAs generally in cancer or regulatory disease roles, but no direct functional or pathological link specific to KRT73-AS1 is confirmed in the latest datasets.
04

Biomarkers

KRT73-AS1 has been discussed as a potential biomarker (see some resource descriptions such as MapMyGenome), but robust clinical validation is lacking as of the latest reports[6]

Beyond the preview

Go deeper on KRT73 antisense RNA 1 (KRT73-AS1).

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Drug pipeline

Full profile access

Explore the programs pursuing this target and their development progress.

  • Drug candidates
  • Developers
  • Development stage

Clinical trials

Full profile access

Follow the clinical studies evaluating therapies directed at this target.

  • Trial design
  • Status
  • Readouts

Competitive landscape

Full profile access

Compare approaches across drug candidates, modalities, and indications.

  • Programs
  • Modalities
  • Indications

Literature & evidence

Full profile access

Investigate the research and source evidence behind target biology and development.

  • Publications
  • Sources
  • Analysis

Patents

Full profile access

Explore patent activity around therapies and technologies addressing this target.

  • Patents
  • Assignees
  • Technologies

Research & analysis

Full profile access

Connect target biology, drug development, and emerging evidence in your research.

  • Biology
  • Development news
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on KRT73 antisense RNA 1 (KRT73-AS1).

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call