Kruppel-like factor 4 pseudogene 1 (KLF4P1)

KLF4 pseudogene 1 (KLF4P1) is a non-coding DNA element classified as a pseudogene of the Kruppel-like factor 4 (KLF4), a key transcription factor involved in cell proliferation, differentiation, apoptosis, and pluripotency[1][2][3][5][6][7]. Unlike its functional parent gene, KLF4P1 does not produce a protein product and has no documented physiological or pathological role. While some pseudogenes are occasionally implicated in gene regulation or as regulatory RNAs, there is no evidence in the current literature that KLF4P1 possesses such activity. Therefore, KLF4P1 is not regarded as a therapeutic target, disease gene, or biomarker. **Note:** All referenced functions and disease associations are linked to the parental KLF4 gene, not the pseudogene KLF4P1. Data on KLF4P1 itself are sparse, and its inclusion as a therapeutic target is incorrect.

Other names

KLF4 pseudogene 1Kruppel-like factor 4 pseudogene 1Kruppel-like factor 4 (gut) pseudogene 1KLF4P1