Kruppel-like factor 7 pseudogene 1 (KLF7P1)

KLF7 pseudogene 1 (KLF7P1) is a genomic DNA sequence with high similarity to the functional gene Kruppel-like factor 7 (KLF7), but it does not code for a protein and does not have biological activity associated with the canonical gene[1]. KLF7P1 is located on the long arm of chromosome 3 as a nonfunctional copy of KLF7[1]. Pseudogenes are often remnants of gene duplication or retrotransposition events and typically lack promoter activity, intronic structure, or other necessary regulatory features for protein expression. For context, KLF7 (not KLF7P1) is a protein-coding gene encoding a zinc-finger transcription factor involved in development, cell proliferation, differentiation, metabolic regulation, and disease roles such as type 2 diabetes, obesity, and cancer[1][2]. The pseudogene KLF7P1 does not share these properties, is not considered a drug target, and has no known aliases, family, functions, disease roles, or drugs associated with it[1]. If you are seeking information on a therapeutic target, you should refer to Kruppel-like factor 7 (KLF7), not KLF7P1.

Other names

KLF7P1Kruppel-like factor 7 pseudogene 1