Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Lactoferrin (LTF)
- Target
- LTF
- Molecular classification
- Transferrins, Glycoprotein
01
Overview
Lactoferrin (LF), also known as lactotransferrin (LTF), is a multifunctional glycoprotein belonging to the transferrin family. It binds iron tightly but reversibly, which plays a crucial role in regulating iron absorption. LF exhibits broad-spectrum antimicrobial properties and modulates immune responses. It also demonstrates anti-inflammatory and anticancer activities. LF is found in various secretory fluids, including milk, saliva, and tears, as well as in neutrophils.
- Other names
- Lactotransferrin
02
Mechanism of action
Iron chelation; membrane disruption; antimicrobial peptide activity; modulation of host immune responses
03
Biological functions
Iron transportAntimicrobial activityImmunomodulationAnti-inflammatory activityAntioxidant activityRegulation of bone marrow functionPromotion of healthy intestinal bacteria populationsWound healing
04
Disease associations
InfectionGastrointestinal disordersIron deficiency anemiaCancerInflammation
05
Safety considerations
Bovine-derived lactoferrin carries minimal risk regarding prion diseasesRecombinant human lactoferrins are often produced using engineered rice or other plant systems
Beyond the preview
Go deeper on Lactoferrin (LTF).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Lactoferrin (LTF).