Target intelligence / Profile preview

Lamin tail domain-containing protein 2 (LMNTD2)

Target
LMNTD2
Molecular classification
Other
01

Overview

Lamin tail domain-containing protein 2 (LMNTD2) is a protein encoded by the LMNTD2 gene in humans and is predicted to be a structural constituent of chromatin as well as to act upstream of, or within, the positive regulation of mRNA splicing via the spliceosome[4][8]. It is predicted to be active in lamin filaments, structures that provide nuclear stability and regulate processes such as transcription and chromatin organization[4]. While LMNTD2 interacts with a number of different proteins, there is currently no published evidence that LMNTD2 itself functions as a therapeutic target, such as a receptor, enzyme, transporter, or similar molecule[4][1]. It is considered a protein-coding gene with chromatin-associated function but is not directly implicated as a drug target, diagnostic biomarker, or disease driver in publicly available data[4][1][5][8]. Notes: - This entry is **not a therapeutic target** in the classical sense (e.g., receptor, enzyme, transporter). - It is **not a receptor or enzyme**, and there is **no evidence of drug interactions** or known mechanisms of action relevant to clinical pharmacology. - The related lncRNA **LMNTD2-AS1** is associated with prostate cancer progression as a potential biomarker, but LMNTD2 (the protein) itself is not[7][9]. - If you are seeking information about the related long non-coding RNA "LMNTD2-AS1," which influences cancer pathways and immune cell infiltration, that is a **distinct biomolecule** from the protein "lamin tail domain-containing protein 2"[7][9]. If your intent was to map a therapeutic target, this entry is likely **incorrect** as LMNTD2 does not fit conventional drug target classes.

Other names
C11orf35MGC35138lamin tail domain containing 2LMNTD2
02

Biological functions

Structural constituent of chromatinPositive regulation of mRNA splicing via spliceosome[4][8]
03

Disease associations

Other

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