Target intelligence / Profile preview

Large ribosomal subunit protein mL38, mitochondrial (MRPL38)

Target
MRPL38
Molecular classification
Ribosomal protein, Mitochondrial ribosome component, Structural protein of large ribosomal subunit (39S), Other
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Overview

Large ribosomal subunit protein mL38 (MRPL38) is a ribosomal protein encoded by the nuclear genome and imported into mitochondria where it functions as a component of the 39S large subunit of the mitochondrial ribosome. Its primary role is as a structural constituent involved in mitochondrial translation, facilitating protein synthesis within the mitochondrion. MRPL38 is localized to the mitochondrion and the cytosol and is essential for proper function of mitochondrial ribosomes necessary for cellular energy production. There are no current indications that MRPL38 is considered a druggable target, nor is there evidence of direct involvement in human disease or therapeutic relevance based on current knowledge.

Other names
MRPL38HSPC262L38mtMRP-L38RPML3MRP-L3MGC4810mL3839S ribosomal protein L38, mitochondrialmitochondrial large ribosomal subunit protein mL38
02

Mechanism of action

Not applicable (not a typical drug target; acts via structural involvement in ribosomal protein synthesis)

03

Biological functions

Structural constituent of ribosomeProtein synthesis within mitochondria (mitochondrial translation)Other
04

Disease associations

Other

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