Target intelligence / Profile preview

LARGE1 antisense RNA 2 (LARGE1-AS2)

Target
LARGE1-AS2
Molecular classification
Antisense long non-coding RNA (lncRNA), Noncoding RNA
01

Overview

LARGE1 antisense RNA 2 (LARGE1-AS2) is predicted to be an antisense long non-coding RNA transcribed from the opposite strand of the LARGE1 gene locus. Antisense long non-coding RNAs can regulate the expression of their sense genes via multiple mechanisms, including modulation of mRNA stability, recruitment of chromatin modifiers, and participation in epigenetic regulation. However, as of now, there is no direct scientific evidence or peer-reviewed research describing the biological function, disease association, or therapeutic relevance of LARGE1-AS2 specifically. Its existence is inferred from genomic annotation, but it is not a characterized molecular target.

02

Mechanism of action

None known

03

Biological functions

Unknown for LARGE1-AS2 specificallyBy analogy with other antisense lncRNAs, possible roles in regulation of gene expression at the transcriptional, post-transcriptional, or epigenetic level, but no data specific to LARGE1-AS2
04

Disease associations

No evidence for involvement in specific diseases has been published for LARGE1-AS2

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