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Left ventricular function

Molecular classification
Other
01

Overview

"Left ventricular function" refers to the ability of the left ventricle (the heart's main pumping chamber) to pump blood efficiently throughout the body. It is typically measured using left ventricular ejection fraction (LVEF), representing the percentage of blood ejected during systole compared to the volume present at the end of diastole[1][4][6][9]. Assessment of left ventricular function is crucial in diagnosing and managing heart failure, ischemic heart disease, cardiomyopathy, and other cardiovascular conditions. It is not itself a protein, receptor, enzyme, or molecular entity, but rather a clinical physiological parameter derived from cardiac imaging or hemodynamic measurements[1][4].

Other names
Left ventricular (LV) functionLV systolic functionLeft ventricular ejection fraction (LVEF)LV functionLeft ventricular performance
02

Biological functions

Cardiac contractilityHemodynamic functionMaintenance of cardiac output
03

Disease associations

Cardiovascular diseaseHeart failureIschemic heart diseaseCardiomyopathyValvular heart disease
04

Biomarkers

Left ventricular ejection fraction (LVEF)End-diastolic volume (EDV)End-systolic volume (ESV)Stroke volumeCardiac output

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