Leucine rich repeat containing 57 pseudogene 1 (LRRC57P1)

Leucine rich repeat containing 57 pseudogene 1 (LRRC57P1) is a presumed nonfunctional copy of the LRRC57 gene. LRRC57 encodes a leucine-rich repeat domain-containing protein that is highly conserved across species and thought to be involved in protein-protein interactions, but its exact biological role is unknown. However, LRRC57P1 refers to a pseudogene: a genomic DNA sequence similar to LRRC57 but not expected to produce a functional protein. There is no evidence that LRRC57P1 encodes a protein, participates in known molecular pathways, acts as a therapeutic target, or associates with disease. Further, the sequence may be misspelled or mistaken for the functional LRRC57 gene; no authoritative databases report LRRC57P1 as a defined gene target. Key clarification: LRRC57 is a valid protein-coding gene encoding leucine rich repeat containing 57, but LRRC57P1 refers to a pseudogene, which is not considered a therapeutic target. There is no evidence of LRRC57P1 having any biological function, disease relevance, interacting drugs, or biomarker value. Summary of issues: LRRC57P1 is not a protein, not a therapeutic target, and is likely a misidentification or incorrect target due to being a pseudogene.

Other names

LRRC57P1leucine-rich repeat containing 57 pseudogene 1