Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Leucine-rich repeat-containing protein 75B (LRRC75B)
- Target
- LRRC75B
- Molecular classification
- Leucine-rich repeat-containing protein, Other
01
Overview
Leucine-rich repeat-containing protein 75B (LRRC75B) is part of the leucine-rich repeat-containing (LRRC) protein family, characterized by multiple LRR motifs that provide a structural framework for protein-protein interactions. The specific biological function of LRRC75B is not fully characterized, but experimental studies in murine muscle cells indicate that it acts as a negative regulator of myogenic differentiation, suppressing the expression of differentiation markers such as myogenin and modulating the phosphorylation state of Erk1/2 (extracellular signal-regulated kinases). Downregulation of LRRC75B promotes muscle cell differentiation, while its overexpression inhibits the process, suggesting a role in early muscle development and cellular differentiation pathways. There is currently no evidence directly linking LRRC75B to specific pathologies, nor are there any drugs targeting this protein or described mechanisms of drug action.
- Other names
- C22orf36FAM211BMGC131773AI646023Leucine-rich repeat-containing protein FAM211BFamily with sequence similarity 211 member BLeucine-rich repeat-containing protein C22orf36
02
Biological functions
Regulation of myogenic differentiation (muscle cell differentiation)Regulation of signal transduction (through ERK1/2 signaling)Other (protein-protein interaction/possible scaffold)
03
Disease associations
Other (no direct disease association in available sources; possible relevance to muscle development or dysfunction by analogy)
Beyond the preview
Go deeper on Leucine-rich repeat-containing protein 75B (LRRC75B).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Leucine-rich repeat-containing protein 75B (LRRC75B).