LIF antisense RNA 2 (LIF-AS2)

LIF antisense RNA 2 (LIF-AS2) is a long non-coding RNA (lncRNA) gene found in humans, transcribed antisense to nearby coding or non-coding regions, and is classified as an antisense RNA. Antisense RNAs such as LIF-AS2 can regulate gene expression at multiple levels, including transcription, splicing, and translation, often by forming RNA-RNA duplexes with complementary mRNA targets or influencing local chromatin state. The LIF-AS2 gene (HGNC:28298, NCBI Gene: 91370) is located on chromosome 22. While LIF-AS2 belongs to a broader class of lncRNAs implicated in cancer and other diseases, no evidence indicates that it encodes a protein or functions as a traditional therapeutic target, receptor, enzyme, or transporter[1][3][8][9].

Other names

TP53LC08