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Target intelligence / Profile preview
LIM domain kinase 1 pseudogene (LIMK1-ps)
- Target
- LIMK1-ps
- Molecular classification
- Pseudogene, Other
01
Overview
LIM domain kinase 1 pseudogene is a nonfunctional segment of DNA that closely resembles the sequence of the LIM domain kinase 1 gene (LIMK1). Unlike the functional gene, the pseudogene does not produce a protein due to disablements such as frameshifts, deletions, or premature stop codons. Pseudogenes can arise via gene duplication followed by subsequent mutations or through reverse transcription of mRNA transcripts. While the functional LIMK1 protein is a serine/threonine kinase involved in cytoskeletal regulation and has disease associations, the LIMK1 pseudogene has no known role in cellular biology or disease and is not a suitable therapeutic target.
- Other names
- LIMK1 pseudogeneLIMK1-ps1LIM domain kinase 1, pseudogene 1
02
Biological functions
Other
03
Disease associations
Other
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