Target intelligence / Profile preview

Lipid metabolic pathway

01

Overview

The term "Lipid metabolic pathway" refers to a complex network of interconnected biochemical processes rather than a single, specific molecular entity that can be targeted pharmaceutically. It encompasses a series of biochemical reactions that facilitate the digestion, absorption, transport, and processing of lipids within the body, involving multiple organs (liver, adipose tissue, intestines) and numerous enzymes, receptors, transport proteins, and regulatory proteins. Due to its broad and multifaceted nature, it is not considered a discrete therapeutic target itself, but rather a system containing many potential drug-targetable components such as HMG-CoA reductase, LDL receptor, and lipoprotein lipase. The nomenclature systems for lipids, such as LIPID MAPS, classify structures but do not identify the pathway as a single target.

02

Biological functions

Digestion of lipidsAbsorption of lipidsTransport of lipidsProcessing of lipidsLipid catabolismLipid anabolismCholesterol metabolism

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