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Lipid raft

Molecular classification: Membrane microdomain, Lipid assembly

Overview

Lipid rafts are small, dynamic assemblies within cellular membranes, enriched in cholesterol and sphingolipids. They serve as organizing centers for signaling molecules and are involved in various cellular processes, including endocytosis, exocytosis, and pathogen entry. Their existence and precise function are still debated.

Other names: Detergent-resistant membranes (DRMs)

Biological functions

Membrane organizationSignal transduction organizationProtein trafficking regulationEndocytosisExocytosisPathogen recognition/entry/egress

Disease associations

Cancer progressionNeurodegenerationInflammationInfection

Safety considerations

Existence remains debatedDifficulties isolating/studying them directlyDefinitions vary across studies

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