Lipoprotein Metabolism

Lipoprotein metabolism refers to the complex processes by which lipoproteins—biochemical assemblies of lipids and proteins—transport hydrophobic lipid molecules (such as cholesterol and triglycerides) through the aqueous environment of plasma. This system is essential for distributing dietary and endogenously synthesized fats throughout the body, supporting cellular energy needs, membrane synthesis, and hormone production.

Other names

Lipid TransportExogenous Lipid PathwayEndogenous Lipid Pathway

Varies depending on the specific drug; includes inhibition of cholesterol synthesis (statins), activation of PPARα (fibrates), inhibition of cholesterol absorption (ezetimibe), inhibition of PCSK9 (PCSK9 inhibitors), reduction of VLDL secretion (Niacin)