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Target intelligence / Profile preview
Lipoma HMGIC fusion partner-like 1 protein (LHFPL1)
- Target
- LHFPL1
- Molecular classification
- Tetraspan transmembrane protein
01
Overview
Lipoma HMGIC fusion partner-like 1 protein (LHFPL1) is a tetraspan transmembrane protein encoded by the LHFPL1 gene, belonging to the lipoma HMGIC fusion partner (LHFP) family, which is a subset of the tetraspan transmembrane protein superfamily. While some LHFP-like genes are implicated in conditions such as deafness and lipoma due to gene fusion or mutations, the specific biological role and disease connections for LHFPL1 remain unclear. Alternatively spliced transcript variants of LHFPL1 have been detected, but their significance is not yet established[1][2][5].
- Other names
- LHFPL tetraspan subfamily member 1LHFP-like protein 1LHFPL1UNQ5824/PRO19643lipoma HMGIC fusion partner-like 1 proteinlipoma HMGIC fusion partner like 1
02
Biological functions
Protein bindingOther (biological validity of alternative splice variants undetermined)
03
Disease associations
Other (mutations in related LHFP-like genes associated with deafness and lipomas, but specific role for LHFPL1 is not established)
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