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Liver fire blazing, known in Traditional Chinese Medicine as Gan Huo, is a pathological syndrome characterized by an excess of 'heat' or 'yang' energy within the Liver functional system [2][8]. It is not a specific molecular target such as a receptor or enzyme, but rather a diagnostic pattern involving the upward surging of hyperactive energy [4][8]. This state typically manifests through physical symptoms like throbbing temporal headaches, red or bloodshot eyes, a bitter taste in the mouth, and irritability or sudden outbursts of anger [2][5][6]. In traditional practice, it is often associated with modern clinical conditions such as hypertension, migraines, and inflammatory eye diseases [9][10]. Treatment involves the use of 'cooling' and 'bitter' herbal medicines, such as Gentiana scabra or Scutellaria baicalensis, which function to purge excess heat and restore the balance between Yin and Yang [14][15].
Purging excess fire and clearing heat from the Liver and Gallbladder meridians to restore physiological equilibrium [8][12][15]
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