Liver function support

The string “Liver function support” does not denote a single, specific molecular target (such as a receptor, enzyme, transporter, or gene). It is a broad clinical concept encompassing supportive strategies and devices intended to assist liver function, particularly in acute liver failure or acute-on-chronic liver failure. Examples include artificial extracorporeal liver support systems like the Molecular Adsorbents Recirculating System (MARS), which performs albumin dialysis to remove protein-bound toxins, and bioartificial liver systems that use living hepatocytes on biomaterial scaffolds to provide limited detoxification and synthetic activity. Because this term is not a discrete molecule or receptor, it should not be treated as a therapeutic “target” entity for drug–target mapping, and a more specific molecular target would be needed for structured curation.

Other names

Liver function supportLiver support

Extracorporeal detoxification via albumin dialysis in artificial liver support systems such as Molecular Adsorbents Recirculating System (MARS). Toxin removal and metabolic support using bioartificial liver devices incorporating living hepatocytes and scaffolds to provide limited synthetic functions.