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Target intelligence / Profile preview
LOC124900208 (ENSG00000200235) is a predicted human gene located on chromosome 5 (140,579,667–140,579,792 on the forward strand) with a single known transcript. Based on current genomic databases, including Ensembl and Bgee, it is annotated as a pseudogene, specifically referred to as HAUS1 pseudogene 1 (HAUS1P1)[1][4][7]. Pseudogenes are typically nonfunctional copies of protein-coding genes and are not known to produce functional proteins or play active roles in biological processes. Supporting Details: - The Ensembl database identifies ENSG00000200235 as a locus with one transcript but does not provide evidence of a protein-coding function or a known biological role[1]. - Bgee associates it with expression in human tissues under the gene symbol AC116353.1 but again without functional annotation[4]. - The Type 2 Diabetes Knowledge Portal refers to this identifier in association with HAUS1P1 and categorizes it as a "nonprotein" or pseudogene[7]. - There is no indication from available resources that it encodes an active receptor, enzyme, or other druggable molecular target. In summary, LOC124900208/ENSG00000200235 is not a recognized therapeutic or functional target, lacks characterization in terms of molecular family, biological function, or disease role, and appears to be incorrectly referenced as a drug target.
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