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Long-Chain Triglycerides (LCTs)
- Target
- LCTs
- Molecular classification
- Lipid, Triglyceride
01
Overview
Long-chain triglycerides (LCTs) are a type of dietary fat composed of three long-chain fatty acids (typically 13–21 carbon atoms each) esterified to a glycerol backbone. They are the predominant form of fat found in most foods and serve as a major source of caloric energy in the human diet, providing approximately 9.2 calories per gram. While not a direct therapeutic target, manipulation of dietary LCT intake can influence metabolism and disease risk.
- Other names
- Long Chain TriglyceridesLCTDietary Fat (Long Chain)LCFA Triglycerides
02
Mechanism of action
N/A (Dietary component, not a drug target)
03
Biological functions
Energy storageEnergy sourceCellular signaling (indirectly via metabolites)Precursor for other lipids
04
Disease associations
ObesityCardiovascular diseaseMetabolic syndromeType 2 diabetesLipid disorders
05
Safety considerations
Excessive intake can lead to weight gain and obesityHigh intake of saturated LCTs can increase LDL cholesterolImbalance in fatty acid composition (e.g., high omega-6 to omega-3 ratio) can promote inflammation
06
Biomarkers
Plasma triglyceride levelsFatty acid composition in adipose tissue
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