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Target intelligence / Profile preview
Long intergenic non-protein coding RNA 106 (LINC00106)
- Target
- LINC00106
- Molecular classification
- Other (specifically, long non-coding RNA)
01
Overview
Long intergenic non-protein coding RNA 106 (LINC00106) is a human long non-coding RNA (lncRNA) that does not encode a protein but plays important roles in transcriptional and post-transcriptional regulation. LINC00106 is upregulated in several cancers, including prostate cancer and hepatocellular carcinoma, where it is associated with increased cancer cell proliferation, migration, poor prognosis, and stemness. Mechanistically, LINC00106 can interact with proteins such as RPS19BP1 and influence key oncogenic pathways such as the p53 signaling axis, promoting cancer development and progression. Though not a classical drug target like a receptor or enzyme, LINC00106 is being studied as a potential biomarker and possible therapeutic target candidate in cancer biology[2][4][5].
- Other names
- CXYorf8NCRNA00106OTTHUMG00000021061
02
Biological functions
Regulation of cell proliferationRegulation of cell migrationRegulation of p53 signaling pathwayRegulation of cancer stemness and metastasis
03
Disease associations
Cancer: Prostate cancerCancer: Hepatocellular carcinomaCancer: Gastric cancer
04
Biomarkers
Prognostic biomarker in prostate cancerPrognostic biomarker in hepatocellular carcinoma
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