Long intergenic non-protein coding RNA 1060 (LINC01060)

Long intergenic non-protein coding RNA 1060 (LINC01060) is a human long non-coding RNA (lncRNA) gene located on chromosome 4 that does not encode a protein[1][3][6]. It represents a subclass of lncRNAs known as long intergenic non-coding RNAs (lincRNAs), which are transcribed from genomic regions not overlapping with protein-coding genes, and are generally longer than 200 nucleotides[7]. While the functions of many lincRNAs remain unclear, LINC01060 has been shown to suppress pancreatic cancer progression by regulating the expression of vinculin, suggesting a potential role in cancer biology, especially as a tumor suppressor[6]. Like other lincRNAs, it may participate in regulating gene transcription, chromatin remodeling, and epigenetic modification, though detailed mechanisms for this specific lncRNA are still under investigation[6][7]. There are currently no known drugs that specifically target LINC01060, and it is not currently classified as a therapeutic target like receptors or enzymes[6][1][3].

Other names

LINC01060long intergenic non-protein coding RNA 1060