Long intergenic non-protein coding RNA 111 (LINC00111)

Long intergenic non-protein coding RNA 111 (LINC00111) is a member of the long non-coding RNA (lncRNA) class, more specifically classified as a long intergenic non-coding RNA (lincRNA). LINC00111 does not encode a protein but is transcribed as a functional RNA molecule. It has emerged as a potential regulator of gene expression, particularly implicated in cancer biology. Studies have found that LINC00111 is involved in the regulation of gene networks associated with tumor progression and immune response, notably in gastric adenocarcinoma associated with *Helicobacter pylori* infection[1]. It has been identified as a promising prognostic biomarker in gastric cancer and has been proposed for diagnostic or therapeutic use in nonsmall-cell lung cancer[2]. Its precise molecular mechanisms typically involve participation in competing endogenous RNA (ceRNA) networks and modulation of signaling pathways such as Wnt, HIF-1, and cytokine interactions[1]. No direct drug interactions or specific mechanisms of action for therapeutic targeting have been reported for LINC00111 as of now[1].

Other names

C21ORF21NCRNA00111