Target intelligence / Profile preview

long intergenic non-protein coding RNA 1192 (LINC01192)

Target
LINC01192
Molecular classification
long non-coding RNA (lncRNA), cancer/testis antigen (CTA), Other (non-protein coding transcript)
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Overview

Long intergenic non-protein coding RNA 1192 (LINC01192, also known as CT64) is a long non-coding RNA that belongs to the class of cancer/testis antigens. It is located on chromosome 3q26.1 and comprises 7 exons. CTAs like LINC01192 are typically expressed in male testicular tissue and are largely silenced in most other normal tissues. Their aberrant expression in various cancers, including lung cancer, links them with cancer cell processes such as growth, survival, metastasis, mitotic fidelity, and resistance to chemotherapeutics. LINC01192 is not known to encode a protein and has no confirmed receptor or enzymatic functions. As a CTA, it is of interest in cancer research for its diagnostic, prognostic, and potential therapeutic value; however, specific functional data and drug targeting information for LINC01192 itself remain incomplete at present.

Other names
CT64cancer/testis antigen 64 (non-protein coding)LINC01192
02

Mechanism of action

No known mechanisms of action for drugs targeting LINC01192 are reported, as there are no established therapeutic agents for this molecule

03

Biological functions

Potential involvement in cell proliferation (based on general CTA roles)Other (specific functions of LINC01192 are not well characterized)
04

Disease associations

Cancer (as a CTA, aberrant expression in cancer, particularly lung cancer and possibly other tumors)Other (uncertain roles in other diseases due to limited data)
05

Biomarkers

Cancer diagnosis and prognosis (general class CTAs, some have shown promise as biomarkers in lung cancer)Other (LINC01192 is not yet a clinically validated biomarker)

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