Long intergenic non-protein coding RNA 1228 (LINC01228)

Long intergenic non-protein coding RNA 1228 (LINC01228) is a human long non-coding RNA (lncRNA) gene located at chromosome 16q23.2 (region chr16:79797826-79827185)[1][3][5]. It is classified as an intergenic lncRNA, a class of non-coding RNAs that do not encode proteins but can regulate gene expression and chromatin structure[9]. While dysregulation or genetic variants in some lincRNAs have been implicated in various cancers and other diseases, there is currently no direct evidence linking LINC01228 specifically to a characterized disease phenotype or as a therapeutic target[9]. LINC01228 may be listed in genome-wide association databases due to its genomic location and potential for containing or being near polymorphisms of interest, but its functional role remains largely undefined[1][7]. There are no known drugs or established biomarker roles for LINC01228, and it is not considered a therapeutic or diagnostic target at this time[5][3][9].

Other names

LINC01228lincRNA-DYNLRB2-2DYNLRB2-AS1ENSG00000261082 (Ensembl)104266962 (NCBI Gene)

Not applicable (no drugs target this lncRNA; no mechanism of action described)