Target intelligence / Profile preview

Long intergenic non-protein coding RNA 1345 (LINC01345)

Target
LINC01345
Molecular classification
Long non-coding RNA, Long intergenic non-coding RNA, Non-protein coding RNA
01

Overview

LINC01345 is a human long intergenic non-protein coding RNA gene, transcribed into a non-coding RNA molecule that does not encode a protein. This lincRNA belongs to the class of non-coding RNAs that are longer than 200 nucleotides and do not overlap known protein-coding genes. While the biological role of LINC01345 remains uncharacterized, lincRNAs in general are implicated in fine-tuning the expression of nearby genes, chromatin structure modulation, and various levels of gene regulation important for tissue specificity and development. Functional characterization and disease associations for LINC01345 have not yet been reported in the scientific literature or gene databases. Emerging research on lincRNAs suggests broad regulatory roles and possible future relevance in cancer and other diseases, but there is no specific evidence and no known drugs acting on LINC01345 to date.

Other names
LINC01345
02

Mechanism of action

Not applicable; there are no drugs known to act directly on LINC01345 or lincRNAs as a class.

03

Biological functions

Chromatin remodeling (general for lincRNAs)Genome architecture regulation (general for lincRNAs)RNA stabilization (general for lincRNAs)Transcription regulation (general for lincRNAs)Enhancer-associated regulatory activity (general for lincRNAs)
04

Disease associations

Cancer (general for lincRNAs)Other (roles are emerging but specific evidence for LINC01345 is lacking)

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