Long intergenic non-protein coding RNA 1385 (LINC01385)

Long intergenic non-protein coding RNA 1385 (LINC01385) is a long non-coding RNA gene located on human chromosome 5. LincRNAs such as LINC01385 do not code for proteins but play regulatory roles in chromatin modification, transcription, and cellular signaling pathways. They are important in development and disease, especially cancer, where many lincRNAs are implicated in progression and metastasis. The biological roles and disease associations of LINC01385 itself remain largely uncharacterized, but the class as a whole is recognized as a promising area for biomarker development and therapeutic intervention. LINC01385 has an Ensembl Gene ID: ENSG00000251604 and Entrez Gene ID: 106144542. Its chromosomal location is on chromosome 5 (5:73,451,497-73,453,395). No specific drugs or clinical biomarkers have been documented interacting directly with LINC01385 as of the current genomics and GWAS databases. In summary: LINC01385 is a long intergenic non-coding RNA implicated as a functional member of lincRNA regulatory pathways, and is considered a potential therapeutic target largely on the basis of what is known for the class of lincRNAs in cancer biology, though its individual function and clinical relevance require further characterization.

Other names

TCONS_00009424

siRNA-mediated knockdown (for lincRNAs in general, not yet shown specifically for LINC01385); RNA-protein interaction inhibitors (potential strategy for lincRNAs in cancer)