Target intelligence / Profile preview

Long intergenic non-protein coding RNA 1387 (LINC01387)

Target
LINC01387
Molecular classification
Long intergenic non-coding RNA (lincRNA), Long non-coding RNA (lncRNA), Other
01

Overview

Long intergenic non-protein coding RNA 1387 (LINC01387) is a long intergenic non-coding RNA (lincRNA), part of a class of RNA transcripts longer than 200 nucleotides that do not overlap with protein-coding genes and lack protein-coding potential[1][3]. LincRNAs, including LINC01387, generally regulate gene expression through mechanisms such as chromatin remodeling, transcriptional regulation, and RNA stabilization, with diverse roles in tissue-specific functions[1][3]. Although some lincRNAs have been functionally linked to human disease and gene regulatory networks, there is currently no direct evidence in the literature supporting LINC01387 as a characterized therapeutic target, nor its involvement in specific disease mechanisms. It is annotated as "putative uncharacterized protein" in some databases, but prevailing scientific agreement indicates it is non-coding, and there is no validated protein product[1][3]. LINC01387 is not a receptor, enzyme, transporter, or classic drug target, but may have regulatory roles in the human genome typical of its RNA class.

Other names
LINC01387C18orf64Putative uncharacterized protein encoded by LINC01387
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Mechanism of action

Not applicable or uncharacterized

03

Biological functions

Chromatin remodelingRegulation of transcriptionRNA stabilizationModulation of neighboring gene expressionOther
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Disease associations

Potential, but uncharacterized; some lincRNAs broadly implicated in cancer, cell regulation, or developmental processes, but there is no direct attribution for LINC01387 in specific diseases based on available evidence
05

Safety considerations

None reported
06

Interacting drugs

None known
07

Biomarkers

None known

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