Long intergenic non-protein coding RNA 1491 (LINC01491)

Long intergenic non-protein coding RNA 1491 (LINC01491) is a human gene that encodes a long intergenic non-coding RNA (lincRNA) [1]. LincRNAs are a subclass of long non-coding RNAs (lncRNAs) that do not overlap with protein-coding genes and are involved in diverse aspects of gene regulation, often modulating transcription and chromatin state [3][5]. LINC01491 itself is not well characterized; its function and mechanism in human biology remain largely unknown. Recent genome-wide association studies (GWAS) have identified genetic variants in the LINC01491 locus associated with increased risk for conditions such as pulmonary arterial hypertension, suggesting a potential, though unconfirmed, role in disease pathogenesis; further research is needed to clarify its biological function and clinical relevance [2]. There are currently no known drugs or therapeutic interventions that specifically target LINC01491.

Other names

LINC01491