Target intelligence / Profile preview

Long intergenic non-protein coding RNA 1533 (LINC01533)

Target
LINC01533
Molecular classification
Long intergenic non-coding RNA (lincRNA), Long non-coding RNA (lncRNA), Non-coding RNA
01

Overview

Long intergenic non-protein coding RNA 1533 (LINC01533) is a human long intergenic non-coding RNA (lincRNA) gene. LincRNAs are a subclass of long non-coding RNAs that are longer than 200 nucleotides and do not overlap annotated protein-coding genes[1][3][7]. These molecules are actively transcribed, typically by RNA polymerase II, and are involved in a variety of biological processes, primarily acting to fine-tune gene expression, modulate chromatin states, and participate in transcriptional and post-transcriptional regulation[3][7]. Some lincRNAs have been linked to tissue-specific gene regulation and disease processes such as cancer; however, the specific biological and clinical functions of LINC01533 remain poorly characterized. No drugs or therapeutics are currently known to target this RNA directly, and there are no established indications for its use as a clinical biomarker or therapeutic target[1]. LINC01533 is known by several aliases, including CTC-360P9.3 and LOC105376899[1].

Other names
CTC-360P9.3LINC01533LOC105376899
02

Biological functions

Regulation of gene expressionChromatin remodelingRNA stabilizationTranscriptional regulationEnhancer-associated activityModulation of neighboring genes
03

Disease associations

Cancer (general lincRNA implication)Other (specific roles of LINC01533 not firmly established)

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