Long intergenic non-protein coding RNA 1622 (LINC01622)

LINC01622 (Long intergenic non-protein coding RNA 1622) is a non-protein coding RNA gene located in an intergenic region of the human genome. It is classified as a long intergenic non-coding RNA (lincRNA), meaning its transcript does not overlap with annotated protein-coding genes and is typically longer than 200 nucleotides[1][7]. The biological function of LINC01622 itself remains unknown; like other lincRNAs, it may be involved in transcriptional or chromatin regulation, but there is no experimental evidence to support a specific function in humans[5][7]. Genome-wide association studies have identified genetic variants in the region of LINC01622 associated with risk for ischemic stroke and cerebral small vessel disease[2][3]; however, whether LINC01622 itself or neighboring genes (such as FOXF2 or EXOC2) mediate this risk is not established[2][3]. No drug interactions, biomarker roles, or specific safety considerations are known for LINC01622. In summary, LINC01622 is a long intergenic non-coding RNA with unknown functional significance; it is not a therapeutic target, receptor, enzyme, or transporter, and current data does not indicate a direct biological or clinical role beyond its potential association with neighboring loci in human disease risk[1][2][3][7].

Other names

LINC01622TCONS_00011202ENSG00000270937