Long intergenic non-protein coding RNA 1644 (LINC01644)

Long intergenic non-protein coding RNA 1644 (LINC01644) is a human long non-coding RNA gene located on chromosome 22 (chr22:47,402,297-47,488,149 on the reverse strand) and is transcribed as an intergenic lncRNA, meaning it does not code for a protein and is found between protein-coding genes[1][3][7]. It has several alternative transcripts and aliases, including LL22NC03-75H12.2. Multiple lines of evidence confirm its non-coding status, with metrics such as PhyloCSF, CPAT, and various protein prediction algorithms consistently indicating no protein-coding potential[1][3]. LINC01644 has been identified in genomic and transcriptomic screens, and while its exact molecular role is unclear, recent studies have implicated it as a potential prognostic biomarker in cancer, especially in ceRNA (competing endogenous RNA) networks, but it is not currently established as a direct therapeutic target, receptor, enzyme, or transporter[4][5]. There are no known drugs targeting LINC01644, and no safety concerns specific to targeting it have been reported in the literature. Its primary molecular classification is as an intergenic long non-coding RNA, with likely regulatory roles but no established enzymatic, transporter, or receptor activity. No misspelling or data issues are noted for this entry; information is limited due to the novelty and uncharacterized nature of this lncRNA.

Other names

LL22NC03-75H12.2ENSG00000218357ENST00000405369NR_109967NONHSAT087346