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Long intergenic non-protein coding RNA 1653 (LINC01653) is a long noncoding RNA gene located in intergenic regions, meaning it does not overlap with protein-coding genomic elements[1][3]. LincRNAs, including LINC01653, are typically longer than 200 nucleotides and do not encode proteins; instead, they are implicated in diverse cellular processes, often via regulation of gene expression, chromatin organization, or interaction with regulatory proteins and microRNAs[5][7]. While dysregulation of various lincRNAs is linked to disease states—especially cancers, autoimmune, and neurodegenerative diseases—specific functional roles or direct disease associations of LINC01653 remain to be clarified in the scientific literature. LINC01653’s potential as a diagnostic or prognostic biomarker, or as a therapeutic target, remains unproven as of current knowledge[1][3][5][7].
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