Target intelligence / Profile preview

Long intergenic non-protein coding RNA 1718 (LINC01718)

Target
LINC01718
Molecular classification
Long intergenic non-coding RNA (lincRNA), Non-protein coding RNA
01

Overview

LINC01718 is a long non-coding RNA gene that is differentially expressed in certain cancers, notably lung cancer, and is a candidate diagnostic biomarker. It is not an enzyme, receptor, transporter, or transcription factor, but rather is classified as a long intergenic non-coding RNA (lincRNA). LINC01718 encodes a long intergenic non-coding RNA molecule, meaning it does not code for a protein and is located between protein-coding genes in the genome. LINC01718 has been proposed as a diagnostic biomarker for lung cancer based on comparative expression analyses in lung cancer tissues versus healthy controls; specifically, it is one of several lncRNAs that show altered expression and strong discriminative power for classifying cancerous samples. While many lincRNAs are implicated in the epigenetic regulation and post-transcriptional modulation of gene expression, the detailed molecular function of LINC01718 remains to be characterized and is the subject of ongoing research. Its utility is primarily in the context of disease biomarker studies rather than as a direct drug target or receptor. In summary, LINC01718 is a biomarker lincRNA, not a protein-coding therapeutic target, and its main significance lies in cancer diagnosis—especially for lung cancer—rather than in direct molecular targeting by drugs.

Other names
LINC01718
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Mechanism of action

Not applicable. No mechanism of action for drugs targeting this molecule is described in the literature

03

Biological functions

Regulation of gene expressionPotential tumorigenesis involvement
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Disease associations

Cancer
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Biomarkers

LINC01718 is identified as a candidate non-invasive biomarker for lung cancer diagnosis—changes in its expression in blood or tissue samples may distinguish cancerous from healthy tissue

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