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Long intergenic non-protein coding RNA 1725 (LINC01725)
- Target
- LINC01725
- Molecular classification
- Non-coding RNA, Long non-coding RNA (lncRNA), Long intergenic non-coding RNA (lincRNA)
01
Overview
Long intergenic non-protein coding RNA 1725 (LINC01725) is a human gene encoding a long intergenic non-coding RNA (lincRNA), a subclass of long non-coding RNAs that are transcribed from regions of the genome more than 200 nucleotides in length and do not overlap protein-coding genes. LincRNAs such as LINC01725 are thought to participate in gene regulation, chromatin remodeling, and epigenetic modification, often exhibiting high tissue specificity in their expression. Although many lincRNAs have been implicated in development and disease, the specific biological function of LINC01725 is not well characterized, but it has been associated with altered expression in liver diseases such as non-alcoholic fatty liver disease (NAFLD) and cirrhosis[1][2][3][5]. No drugs are known to target LINC01725, and it is not currently regarded as a validated therapeutic target.
- Other names
- LOC101927560LINC01725
02
Mechanism of action
Not applicable, as no drugs are known to target LINC01725.
03
Biological functions
Chromatin remodelingRegulation of gene expression (cis- and trans-acting)RNA stabilizationEpigenetic modificationTranscriptional regulation
04
Disease associations
Liver disease (NAFLD, cirrhosis)Other (potential, as lincRNAs are often dysregulated in cancer and various diseases, but no direct disease role for LINC01725 is confirmed)
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